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Read previewHarvard researcher Dr. David Sinclair has found himself at the center of controversy within the longevity community. He's also earned his share of critics who say his research isn't always backed up by sufficient evidence. Animal Biosciences reissued a press release walking back the "reverse aging" claim. But scientists in the field say the issue is even more fundamental: There's no way to reverse aging, much less measure it. That means debates about the semantics of aging will only become more relevant to our daily lives.
Persons: , David Sinclair, Sinclair, He's, Dr, Nir Barzilai, Matt Kaeberlein —, Matt Kaeberlein, Barzilai, it's, it'll, Andrea Maier, Jeff Bezos, Peter Thiel Organizations: Service, Business, Street Journal, Animal Biosciences, Newsweek, The Academy for Health, Academy for Health, Academy, National Institute, Aging, MIT Technology, National University of Singapore, Longevity
AdvertisementMy free biological age calculation estimated my risk of premature death or diseaseMy biological age test used 9 different measurements taken from blood samples. Tamar Dundua/Getty ImagesAt its essence, any good biological age test is trying to capture the fitness of your body parts. Some of the most respected biological age tests are epigenetic clocks, sometimes called DNA methylation tests. Other clocks incorporate external factors like smoking history, or chronological age into a biological age calculation. The benefits of free biological age testingLearning your own biological age is one simple way to approximate how well your body is weathering the test of time.
Persons: , who's, David Sinclair's, I'm, Tamar Dundua, Dr, Nour Makarem, Makarem, they're, Hilary Brueck, It's, that's, Steve Horvath Organizations: Service, Tally, Business, Columbia University
AdvertisementWinter is part of a growing group of family office principals, including heirs like himself and first-generation entrepreneurs, who are making direct investments in pursuit of longer and healthier lives. They are in good company; longevity startups drew global investment of more than $5.2 billion in 2022 , according to a venture capital firm, Longevity Tech Fund, which used PitchBook data. She and some of her clients are investors in Maximon, a Switzerland-based longevity fund that includes "healthspan clinics" in its portfolio. Eric Becker, cofounder of wealth manager Cresset , and his two sons founded a family office and picked Blue Zone Foods as its first investment. Courtesy of CressetFor Becker, whose daughter died of leukemia at 21, and his family, longevity is not an abstract topic.
Persons: Maximilian Winter, doggedly, Lyme, Fritz Winter, Peter Thiel, There's, Peter Fioretti, David Sinclair, Kathrin Genovese, ultrarich, Genovese, Eric Becker, Cresset, Dan Yadegar, Becker, Johnny Walker Organizations: Longevity Tech Fund, Harmonix, Biotech, UBS, Winter's Harmonix Fund, Blue, Foods, Becker Venture Partners, Newpath Partners Locations: Santa Barbara, Quinta , California, Maximon, Switzerland, Zurich
In "Natalia Speaks," the second season of the documentary series currently available to stream on Max, Natalia Grace tells her side of the story. TruDiagnostic's assessment indicated that Natalia's biological age was close to 22. In theory, the older your biological age, the more likely you are to develop age-related diseases such as cancer or dementia. AdvertisementSome longevity researchers believe there are ways to "reverse" our biological age. For example, Steve Horvath, who invented a way to measure biological age, says he reversed his biological age by 4 years by eating less sugar and more vegetables, quitting smoking, and exercising more.
Persons: , Natalia, Max, Natalia Grace, Michael, Kristine Barnett, Kristine, Antwon, Halland Chen, Timothy Gossweiler, Gossweiler, Katherine Barnett, Clouse, Steve Horvath, David Sinclair, Sinclair, it's Organizations: Service, Business, National Institute, Aging, Research Locations: Indiana, Canada, Harvard
It seems like just about everyone wants to know how to live longer, healthier lives these days, especially as more 100-year-olds speak out about how happy and fulfilled they are. 'How to Improve Your Healthspan Using DNA Insights with Dr. Bartek Nogal' on Longevity by DesignListen here Longevity by Design aims to speak directly to people hoping to live longer, healthier lives. In a recent episode of the podcast, Gil Blander, recurring host with expertise on longevity, interviews Bartek Nogal, a scientist who researches genetics, about the links between genes and aging. "Knowing your genetic predispositions to certain traits can help you fine tune your wellness plan, and Dr. Nogal and Dr. Blander explain how to do so in this episode," a description of the episode explains. 'The Small Molecules of Longevity' on Human Longevity Podcast
Persons: Radiolab, It's, Gnanasambandan, Marc Wittmann, David Eagleman, Lewis Howes, David Sinclair, Casey Means, Howes, Peter Attia's, ZOE, Jonathan Wolf, Peter Attia, Wolf, Bartek, Gil Blander, Bartek Nogal, Nogal, Blander Organizations: Institute for Frontier, Mental Health, The, ZOE Science, Nutrition, Design Locations: Germany, Harvard
In case you missed it: This is the last week of 10 Things in Tech. The EV company only has six gigafactories across the world: Fremont, California; Sparks, Nevada; Berlin; Shanghai; Austin, Texas; and Buffalo, New York. Each location is outfitted with solar panels, and Musk claims 100 gigafactories could supply the world with all of its energy. My colleague Graham Rapier takes us into the world of Tesla's gigafactories and breaks down what their futures could look like. In a world of remote work, they're trying to pay people the least amount of money to get work done (think freelancers and contractors).
Persons: I'm, Siu, let's, Elon Musk, Graham Rapier, gigafactories, Tyler Le, Allbirds, M0.0nshot, Gigi Chow, Elon Musk's, Walter Isaacson, it's, David Sinclair, Lewis Joly, cardiologists, Eid Mubarak, Diamond Naga Siu, Alistair Barr, Hallam Bullock Organizations: it's, EV, Employers, Paris Air, Storm Shadow, Interactive Entertainment, Tencent Locations: Tech, Fremont , California, Sparks , Nevada, Berlin, Shanghai, Austin , Texas, Buffalo , New York, Silicon, San Francisco, Croatia, Dubrovnik, Harvard, Le Bourget, Paris, France, Ukraine, New York, Florida, Barcelona, Spain, San Diego, Silicon Valley, London
Private credit goes Hollywood. A town that loves a good story has a leading role in the biggest one on Wall Street. So in that vein, private credit filling the gap left by banks reconsidering their lending decisions is great. Ratings agency Moody's has already raised the alarm, suggesting defaults among borrowers in private credit will rise. But I think it's fair to say that industry isn't as cut and dried as others private credit might be lending to.
Persons: Dan DeFrancesco, fanny, , we've, Maks, it's, Insider's Reed Alexander, Rebecca Ungarino, Reed, Rebecca, Moody's, Consuelo Vanderbilt Costin, Bryan Griffin, James, Jim, Crown, Henry Crown, Junius Myer Schine, David Sinclair, Jeffrey Cane, Hallam Bullock Organizations: Credit Suisse, Wall, Investment, Hollywood, Creators, The Vanderbilt, UBS, JPMorgan, Fidelity, Wall Street, LinkedIn Locations: Hollywood, Swiss, Aspen , Colorado, Silicon, Jersey Shore, New York, London
And start-ups like Tally Health are promising to provide that insight into how we age and, potentially, how to get ahead of it. Tally Health created and administers a test that collects DNA samples from a cheek swab, and calculates what the company calls a "biological age." "We call it the credit score for the body that measures all aspects of your health," Dr. David Sinclair, a Harvard scientist and longevity expert, tells CNBC Make It. Sinclair co-founded Tally Health and, as its scientific advisor, had a hand in creating its test which partly relies on his years of research in the field of longevity. I was offered the opportunity to take the "TallyAge Test" and despite my generally healthy lifestyle, I was still a bit nervous to learn my biological age.
Here's a list of fruits, vegetables, spices, and drinks that experts say can lead to a longer life. Others, like biotech entrepreneur Bryan Johnson, methodically prepare smoothies with compounds like creatine, spermidine, collagen peptides, and consume copious amounts of vegetables. Still, those like Johnson aren't abiding by fastidious nutrition plans simply to stay healthy — they're aiming to live longer. Breaking it down to the cellular levelVinjamoori said that it can also be helpful to think about eating for longevity from the cellular level. Insider set out to figure exactly which foods would optimize those processes, and ultimately, help you live longer.
Members of R360, a club with a $100 million net-worth minimum, are also exploring longevity. Tests revealed he had an arterial blockage and that his cardiac system was that of a 68-year-old, Fioretti told Insider. Fioretti co-chairs a group of 25 ultra-rich individuals who seek to push the limits of the human lifespan. Though the group's main focus is longevity, members have also learned more about psychedelic drugs as treatments for addiction and mental health. Some R360 members have independently invested in anti-aging endeavors, including Fioretti.
It is widely believed, and backed by science, that women outlive men, but there is new talk of the role your height might play in longevity — specifically, shorter people may live longer than taller people. Here are their theories about why shorter people may live longer than their opposites. The lifespans of shorter people appear to be longer than their taller counterparts, the paper says. David Sinclair Co-founder and Scientific Advisor of Tally HealthYet, height isn't the only reason women live longer. Robine's hypothesis for why women live longer is simply this: "Women are more resistant to mortality [and] to death than men because they are just resisting more to difficulties."
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